For Pancreatic Islet Isolation and Other Dissociation
Description
Neutral Protease NB is a metalloprotease suitable for tissue dissociation applications.
This enzyme cuts diverse peptides in front of hydrophobic amino acids and thereby creates smaller fragments. For cell isolation, Neutral Protease NB is often used in combination with purified Collagenase NB 1 Premium Grade as well as Collagenase NB 4 Standard Grade or Collagenase NB 8 Broad Range. If cells are intended for transplantation into humans, Neutral Protease NB GMP Grade is recommended.
Related Products
Neutral Protease NB is often used in combination with Collagenase NB 1 Premium Grade, but Neutral Protease NB can be combined with other collagenases like Collagenase NB 4 Standard Grade or Collagenase NB 8 Broad Range as well. For applications with GMP requirements, Nordmark offers Neutral Protease NB GMP Grade, which can be used in combination with Collagenase NB 1 GMP Grade. Along with the Collagenase NB product line, Nordmark also offers animal-free products, Neutral Protease AF GMP Grade and Collagenase AF-1 GMP Grade, which are completely free of any animal-based components, thereby excluding the risk of transmission of potential animal-derived pathogens.
Specifications
Origin |
Clostridium histolyticum |
Composition |
|
Molecular weight |
34 kDa |
Activities |
Neutral Protease activity: ≥ 0.50 U/mg (DMC assay) |
Storage conditions |
+2 °C to +8 °C |
Shipping conditions |
Cooled on blue or dry ice depending on the destination |
Intended use |
For research use only |