Neutral Protease AF GMP Grade – Witec AG

Art No | N0003553
770.00 CHF
770.00 CHF
Brochure

Size: ≥ 100 DMC

For Cell Isolation from Pancreas, Adipose Tissue and Tumors

 

Description

Neutral Protease AF GMP Grade is derived from C.histolyticum using a production process completely free of any animal-based components. Thus, any risk of transmission of potential animal-derived pathogens is excluded.

This purified metalloprotease is suitable for the dissociation of tissue in clinical applications. For especially gentle cell isolation it is recommended to use Neutral Protease AF GMP Grade in combination with highly purified Collagenase AF-1 GMP Grade. Here, it has been shown to be highly effective for the isolation of islets of Langerhans from human pancreas intended for transplantation and stromal vascular fraction (SVF) from adipose tissue and tumor cells.

Supplier

Nordmark Pharma GmbH
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Specifications

Origin

Clostridium histolyticum

Composition

Neutral Protease

Molecular weight

34 kDa

Special features

Manufactured free from animal components & according to international GMP guidelines

Microbiological examination

Endotoxin:
Sterility (Ph. Eur.)
Absence of Clostridia
TAMC (Total Aerobic Microbial Count) ≤ 10/Vial
TYMC (Total Yeasts/ Moulds Count) ≤ 10/Vial

Activities

Neutral Protease activity:  ≥ 0.50 U/mg lyophilisate (DMC assay)

Storage conditions

+2°C to +8°C

Shipping conditions

At ambient temperature

Intended use

For clinical applications

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