Webinars – Witec AG

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Past webinars

PacBio - Smoking Out Structural Variants in the Cannabis Genome

Please register to attend; thank you.

The legal California cannabis market is expected to be larger than the top 5 agricultural products combined in that state due to its fast growth and diverse use in fiber, food, and pharmaceutical generation. Unlike many outdoor grown crops, THCA and CBDA dominant cannabis strains are predominantly grown indoors at high expense (>$500/pound), placing an intense focus on the genetics of yield enhancement.

As a contribution to those efforts, Medicinal Genomics recently published the most comprehensive and complete cannabis genome assembly of a Type II (THCA and CDBA producing) plant known as Jamaican Lion. This work revealed a very complex tandem array of over 30 cannabinoid synthase genes separated by 30 kb, 60 kb & 90 kb long terminal repeats that are likely playing a role in gene duplication and enhanced expression.

To more completely characterize variants associated with cannabinoid synthase gene structures, we sequenced Type I, II, and III plants with PacBio long reads and identified type-specific structural variants.

Join our speakers as they share the latest advances in cannabis genomics, including:

  • How PacBio long-read sequencing enables high-quality genomics research in plants
  • High-quality annotation of the cannabis reference genome using full-length transcript sequencing
  • New insights into cannabinoid synthesis across different types of cannabis plants

Speakers:

Sarah Kingan, Ph.D.
Staff Scientist, Bioinformatics
PacBio

Kevin McKernan
Founder and Chief Science Officer
Medicinal Genomics

Date & Time

18.06.2019
6 p.m. Swiss time

PacBio - Sequence with Confidence: Introducing the Sequel II System

PacBio is excited to announce the release of the Sequel II System which increases the throughput of Single Molecule, Real -Time (SMRT) Sequencing by approximately 8-fold. The Sequel II System builds upon the recent advances of the Sequel System, to deliver highly accurate long reads with over 99% single-molecule accuracy.

Join us to hear our early access customers share their experiences and results generated with the Sequel II System.

Date: Wednesday, June 5, 2019
9:00 a.m. PDT
12:00 p.m. EDT
5:00 p.m. BST
6 p.m. Swiss time

Please register to attend; thank you.

This webinar will explore:

  • Early access customers’ experience with their Sequel II Systems
  • How the Sequel II System delivers highly accurate long reads
  • The featured applications of the Sequel II System

Speakers:

Luke J. Tallon
Scientific Director, Genomics Resource Center
Institute for Genome Sciences
University of Maryland School of Medicine

Shane A. McCarthy, Ph.D.
Senior Research Associate
University of Cambridge

Kiran Garimella, Ph.D.
Senior Computational Scientist
Broad Institute of MIT and Harvard University

PacBio - Streamline your library preparation with the SMRTbell Express Template Prep Kit 2.0

Join Pacbio's webinar to learn about procedures and checklists for preparing multiplexed microbial libraries and gDNA libraries using the SMRTbell Express Template Preparation Kit 2.0.

Date: Wednesday, May 22, 2019
10:00 a.m. New York City
3:00 p.m. London
4:00 p.m. Paris | Zurich
5:00 p.m. Helsinki

Please register to attend; thank you.

The SMRTbell Express Template Prep Kit 2.0 provides a streamlined, single-tube reaction strategy to generate SMRTbell libraries from 500 bp to >50 kb insert size targets to support large-insert genomic libraries, multiplexed microbial genomes and amplicon sequencing.

With this new formulation, which delivers libraries in 4 hours’ time, we have increased both the yield and efficiency of SMRTbell library preparation for SMRT Sequencing, while further minimizing handling-induced DNA damage to retain the integrity of genomic DNA (gDNA).

In this webinar we will:

  • Review two procedures and checklists available to prepare multiplexed microbial libraries and gDNA libraries
  • Discuss the key benefits and performance of the currently supported protocols through examples
  • Provide an update on the preparation of low input DNA libraries starting from 100 ng input material now available

Speaker
John Baeten
Field Applications Scientist, PacBio

Date & Time

22.05.2019
4 pm CH time

Unlock the potential of your SMRT Sequencing data with SMRT Link

Join our webinar to learn how to use PacBio SMRT Link software to review result metrics and performance trends of your library and Sequel System run, and how to start basic analysis.

Date: Wednesday, March 13, 2019

11:00 a.m. New York City
3:00 p.m. London
4:00 p.m. Paris
5:00 p.m. Helsinki

A Single Molecule, Real-Time (SMRT) Sequencing run on the Sequel System can generate up to 50 Gb per SMRT Cell with average read lengths of up to 30 kb. The amount of data generated and the number of applications available highlight how important the quality control of a sequencing run is before starting any bioinformatic analysis.

SMRT Link is a graphical software application, designed for low- or high-throughput labs. It guides you through all steps of your Sequel System run, including run QC and secondary analysis, to make the most of your data before transferring them eventually to a bioinformatician.

In this webinar:

  • We will review the key metrics and plots in SMRT Link to QC sequencing library and run on the Sequel System.
  • We will discuss the main SMRT Analysis applications, including demultiplexing of barcoded datasets, generating CCS reads, and starting a de novo assembly.

This will be a technical discussion for scientists with SMRT Sequencing data who would like to use the graphical interface of SMRT Link. No data analysis or command line background is required.

Speakers:

Déborah Moine
Field Applications Scientist, PacBio

David Stucki
Field Applications Scientist - Bioinformatics, PacBio

Complete Genomes within Reach: Closing Bacterial Genomes from the Lakes of Minnesota to NYC Hospitals

Highly accurate, closed bacterial genomes allow you to see both the SNPs and structural variations that drive the biology that matters to you, including AMR and virulence in clinical applications and metabolic adaptations in environmental isolates. With PacBio sequencing you can assemble through repetitive regions to reveal hidden biology, including insertion sequence elements and synthetic gene clusters.

Join our speakers as they share the latest advances in Single Molecule, Real-Time (SMRT) Sequencing, including:

  • Details of the newly updated microbial whole genome sequencing pipeline, which leverages the multiplexing capabilities of the Sequel System to provide PacBio genomes at lower cost.
  • New insights into the ecophysiology of Minnesota microbes using long-read sequencing.
  • An understanding of how whole genome sequencing is used in pathogen surveillance programs at hospitals.

Speakers:

Benjamin Auch, M.Sc.
Research Scientist
Innovation Lab, University of Minnesota Genomics Center

Cody Sheik, Ph.D.
Assistant Professor of Biology
University of Minnesota Duluth

Harm van Bakel, Ph.D.
Assistant Professor of Genetics and Genomic Sciences
Icahn School of Medicine at Mount Sinai

We look forward to your participation as you learn about SMRT Sequencing and the new, lower-cost option for generating PacBio microbial genomes on the Sequel System.

 

Protein Sample Evaluation using the NanoDrop™ One UV Vis Spectrophotometer

On September 18th, 2018 at 4pm (EDT)

you have the opportunity to join the online event

"Protein Sample Evaluation using the NanoDrop™ One UV Vis Spectrophotometer"

Presenter:

Voula Kodoyianni, PhD, MS
Product Marketing Manager | UV-Vis and Fluorescence Instruments | Thermo Fisher Scientific

We know from VOC that 83% of our customers quantify proteins with a spectrophotometer at least once per week. There is a lot of helpful information in this webinar for scientists who work with proteins. Concepts covered and clarified are:

  • Protein mass extinction coefficients vs molar extinction coefficients
  • Blank vs background correction
  • How to use “sample type options”
  • “Good” and “bad” buffers for protein A280
  • How to customize their instrument using the Protein Editor and Dye Editor
  • How the Proteins and Labels application quantifies both the carrier protein and the FLR label
  • and more...

If you are interested, please register online.

Date & Time

18.09.2018
16.00 am (EDT)

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