LeviSelect Human CD45+ Depletion Kit – Witec AG

For oncology or immuno-oncology research, the LeviSelect CD45 Depletion Kits provide a highly effective method for enriching pure tumor cells enabling characterization for drug discovery and biomarker identification.

Human or mouse CD45+ cells are depleted from a mixture of cells in parallel with viable cell enrichment on the LeviCell system. CD45+ cells are retained in the LeviCell cartridge, while CD45- cells of interest remain label-free and are collected for further downstream analysis.

How it works

LeviSelect products combine Levitation Technology with targeted selection of specific cell types. Targeted and viable cell enrichment are performed simultaneously on the LeviCell system. By combining the natural density and magnetic susceptibility of cells within a paramagnetic compound with the addition of antibodies conjugated to nanospheres of different densities, cells can levitate at different heights. This process allows the separation of specific cells of interest from unwanted cells during a single LeviCell run.

Identifying and enriching cells of interest from mixed cell populations is fundamental to studying disease models and basic cell biology. Levitation Technology provides the gentlest cell enrichment method, preserving target-specific cells of interest unbiasedly.

LeviSelect Depletion and Enrichment Kits

LeviSelect Kits provide a fast and efficient method to deplete a specific cell type away from a mixture of cells or remove several cell-specific populations to enrich for a target cell of interest (negative selection). In both kit types, the target cell of interest remains label-free, ensuring cells are not perturbed.

Obtain gentle enrichment of viable target-specific populations, which remain untouched within the LeviCell cartridge. Now, you can achieve dying or dead cell removal – plus removal of debris – in a single LeviCell run.