STOmics Stereo-seq Transcriptomics Set for Chip-on-a-slide - 1x1cm

Art No | 211ST114

STOmics Stereo-seq Transcriptomics Set for Chip-on-a-slide - 1x1cm

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Unveiling the Inner Workings of Tissues: Stereo-seq Transcriptomics Solution

Description

Revolutionize your understanding of gene expression with the Stereo-seq Transcriptomics Solution.

This innovative technology offers unparalleled resolution and field of view, allowing you to map the entire transcriptome (set of RNA molecules) within a tissue section, down to the level of individual cells.

STOmics Stereo-seq Transcriptomics Set for Chip-on-a-slide enables a “tissue-to-data” solution through in situ capture of the whole transcriptome, at nanoscale resolution and centimeter-sized field of view.

Stereo-seq Transcriptomics Solution utilizes DNB patterned array chips loaded with spatially-barcoded probes that capture and prime poly-adenylated mRNA from tissue sections in situ. Each cDNA synthesized from mRNA captured on a particular spot is linked to its spatially-barcoded probe, allowing subsequent gene expression mapping of a tissue section following sequencing and visualization analysis using the StereoMap visualization platform.

Chip sizes: 0.5 x 0.5cm | 1 x 1cm | 1 x 2cm | 2 x 2cm | 2 x 3cm
Spot size: 0.22µm
Center-to-center: 0.5um
Field of view: 132 x 132mm

Highlights

Unbiased in situ capturing of the whole transcriptome with true nanoscale resolution

Proprietary cell segmentation algorithm integrated on Stereo-seq Analysis Workflow (SAW) transforming data to information

Unlimited by species and tissue types, also compatible with both fresh frozen and PFA fixed samples for a more extensible application

Larger capture area with chip sizes up to 1cm by 1cm without compromising the capture efficiency

Workflow

Tissue to Data End-to-End Solution

Advance towards a more accurate and in-depth saptial single-cell omics study with Stereo-seq’s robust chemistry and efficient bioinformatics tools.

Nuclei-stained Image

Spatially Resolved Gene Expression Profile

Single-Cell Clustering Results (via cellbin)

Unprecedented Detail, Powerful Insights:

See Every Cell: Explore tissues at an incredible nanoscale resolution, uncovering the unique genetic activity of each cell.
Large-Scale View: Analyze gene expression across expansive areas of tissue, providing valuable context for your research.
“Tissue-to-Data” Efficiency: Obtain comprehensive transcriptome data directly from tissue samples (in situ), eliminating the need for complex cell isolation procedures.

Publications

Spatiotemporal mapping of gene expression landscapes and developmental trajectories during zebrafish embryogenesis

Single-cell Stereo-seq reveals induced progenitor cells involved in axolotl brain regeneration

Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays

Single-cell spatial transcriptome reveals cell-type organization in the macaque cortex

Supplier

STOmics
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Specifications

Description	For generating a spatially-resolved 3’ mRNA library from biological tissue sections
Kit includes	Stereo-seq Transcriptomics T Kit – 4 RXN Stereo-seq Chip T Slide (1cm*1cm) – 4 EA STOmics Accessory Kit – 5PCS