Sequel™ System – Witec AG

Art No | 100-426-900
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SEQUEL - accelerate your research with the most comprehensive view of genomes, transcriptomes, and epigenomes from our higher-throughput system.


The scalable platform for Single Molecule, Real-Time (SMRT) Sequencing

Accelerate your research with the most comprehensive view of genomes, transcriptomes, and epigenomes from our higher-throughput system. Reduce project costs and timelines as you create higher-quality whole genome assemblies and explore the full size-spectrum of genetic variation.

SEQUEL SYSTEM: high-throughput, cost-effective access to SMRT Sequencing

The new Sequel System is based on our proven Single Molecule, Real-Time (SMRT) technology and delivers about 7X more reads with 1 million zero-mode waveguides (ZMWs) per SMRT Cell. The Sequel System is ideal for projects such as rapidly and cost-effectively generating high-quality whole genome de novo assemblies.

This innovative sequencing system features automated reagent and SMRT Cell handling and an integrated software suite.

The Sequel System has two primary user access points:
Sequel touchscreen interface (for initiating and monitoring runs)
Sequel workdeck (for loading samples, SMRT Cells, reagents, and disposables)

Additional features of the Sequel System include:
Intuitive run setup and monitoring tools
Run-time flexibility (from 30 minutes to 10 hours per SMRT Cell)
Run-size flexibility (from 1 to 16 SMRT Cells per run)
Robotic workflow management


SMRT Sequencing is built upon two key innovations: zero-mode waveguides (ZMWs) and phospholinked nucleotides. ZMWs allow light to illuminate only the bottom of a well in which a DNA polymerase/template complex is immobilized. Phospholinked nucleotides allow observation of the immobilized complex as the DNA polymerase produces a completely natural DNA strand.

The SMRT Sequencing advantage

SMRT Sequencing is ideal for a variety of research applications and offers many benefits, including:

  • Longest average read lengths
  • Highest consensus accuracy
  • Uniform coverage
  • Simultaneous epigenetic characterization
  • Single-molecule resolution


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Operating Temperature

19ºC – 25ºC ± 2°C per hour


20% – 80%, noncondensing


HVAC capacity of up to 13,956 BTU (4090 Watts)


50 PSI (2,585 torr)


92.7 x 86.4 x 167.6 cm


354 kg


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