Personal multi-channel bioreactor with non-invasive real time biomass
Description
The RTS-8 is a personal bioreactor that utilizes patented Reverse-Spin® technology that applies non-invasive, mechanically driven, low energy consumption, innovative type of agitation. Cell suspension is mixed by the single-use falcon bioreactor tube rotation around its axis with a change of direction of rotation motion resulting in high efficient mixing and oxygenation for aerobic cultivation.
- Parallel cultivation of 8 tube bioreactors enables to save time and resources for bioprocess optimization
- Individually controlled bioreactor accelerates optimization process
- Possibility to cultivate microaerophilic and obligate anaerobic microorganisms (not strict anaerobic conditions)
- Reverse–Spin® mixing principle enables non-invasive biomass measurement in real time
- Near-infrared optical system makes it possible to register cell growth kinetics
- Free of charge software for storage, demonstration and analysis of data in real time
- Compact design with low profile and small footprint for personal application
- Individual temperature control for bioprocess applications
- Active cooling for rapid temperature control, e.g. for temperature fluctuation experiments
- Task profiling for process automatization
- Cloud data storage to remotely monitor the process of cultivation while at home or using a mobile phone
SOFTWARE FEATURES
- Real–Time cell growth logging
- 3D graphical representation of OD or growth rate over time over unit
- Pause option
- Save/Load option
- Report option: PDF and Excel
- Remote monitoring option (requires internet connection)
- Cycling/Profiling options
- User manual calibration possibility for most cells
TYPICAL APPLICATIONS
- Fermentation real time growth kinetics
- Clone candidate screening
- Protein expression
- Temperature stress and fluctuation experiments
- Media screening and optimization
- Growth characterization
- Inhibition and toxicity tests
- Strain quality control
- Initial bioprocess optimization studies
Specifications
| Light source |
Laser |
| Measurement wavelength (λ) |
850 ± 15 nm |
| Measurement range |
0-100 OD600 |
| E.coli factory calibration measurement range |
0-50 OD600 |
| S.cerevisiae factory calibration measurement range |
0-75 OD600 |
| Achievable user calibration measurement error (range 0.1-6 OD600) |
± 0.3 |
| Achievable user calibration measurement error (range 6-50 OD600) |
≤ 5% |
| Achievable user calibration measurement error (range 50-75 OD600) |
≤ 10% |
| Measurement periodicity per hour |
1-60 |
| Temperature setting range |
+15°C … +60°C |
| Temperature control range |
+15 °C below ambient … +60 °C |
| Temperature stability |
±0.3 °C |
| Sample temperature accuracy (20°C – 37°C) |
±1 °C |
| Tube sockets |
8 |
| Sample working volume range |
3–50 ml |
| Speed control range |
150–2700 rpm |
| Reverse spin time setting range 150-250 rpm |
0 s |
| Reverse spin time setting range 250–300 rpm |
2-60 s |
| Reverse spin time setting range 300–2700 rpm |
0-60 s |
| Display |
LCD |
| Minimum PC requirements |
|
| Dimensions (W×D×H) | Weight |
350 x 690 x 300mm | 20kg |
| Power consumption |
500W |